supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Phospholipids
supplement:
Conjugated Linoleic Acid
Research Papers that Mention the Interaction
“Compared with oleic acid, Δ9 and Δ6 desaturation indices in plasma phospholipids are decreased after consumption of c9,t11 or t10,c12 CLA.”
Effects of specific CLA isomers on plasma fatty acid profile and expression of desaturases in humans“The CLA isomer content of serum TAG, phospholipids , and total lipids increased 2–5 times with CLA supplementation (P<0.05).”
“In HUVEC, GPx and PHGPx mRNA were increased circa twofold with increasing CLA concentrations although enzyme activity was unchanged.”
“Distribution of 14C-AA among phospholipid classes was altered by CLA treatments in both cell lines.”
“ CLA treatment markedly decreased D9 desaturation index of phospholipids of erythrocyte membrane, hepatic tissue and plasma.”
“ CLA also significantly lowered the incorporation of [14C]-acetate into phospholipid in breast cancer cells, supporting the view that CLA inhibits fatty acid biosynthesis through the interaction with FAS.”
“Moreover, trans-10,cis-12 CLA treatment reduced cis-11 18∶1 concentrations in both neutral lipids and phospholipids while increasing cis-9 18∶1 and 18∶2 concentrations.”
“ CLA supplementation significantly increased all CLA isomers measured in hepatic neutral lipids and phospholipids (P < 0.05).”
Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice.“In addition, increasing dietary CLA was associated with reduced linoleate in hepatic phospholipids.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback