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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phospholipids
supplement:
Bergenin
Research Papers that Mention the Interaction
“Results: The limited absorption of BN was significantly improved in both ex vivo everted rat gut sac model and in vitro Caco-2 cell model when combined with phospholipid.”
“The transport of BPC was uppermost 5.19-fold higher than that of BN.”
Investigation of the mechanisms of improved oral bioavailability of bergenin using bergenin–phospholipid complex“By in situ single-pass intestinal perfusion, the membrane permeability of BN from BNPC-SD was higher than that of BN given alone and was improved further by co-administered verapamil.”
“Cmax and AUC0 → t values for BN were significantly higher for BNPC-SD than for BN given alone and were increased further by verapamil.”
Evaluation of Intestinal Absorption and Bioavailability of a Bergenin–Phospholipid Complex Solid Dispersion in Rats“Conclusion:The BPC is a valuable delivery system to enhance the oral absorption of bergenin.”
“The Cmax and AUC0→∞ of BPC were increased, and the relative bioavailability was significantly increased to 439% of bergenin.”
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