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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phosphocreatine and Creatine Monohydrate

Research Papers that Mention the Interaction

Studies have consistently indicated that CM supplementation increases muscle creatine and phosphocreatine concentrations by approximately 15–40%, enhances anaerobic exercise capacity, and increases training volume leading to greater gains in strength, power, and muscle mass.
Amino Acids  •  2011  |  View Paper
The mechanism by which supplementary creatine could have potential ergogenic effects would be an increased muscle creatine and phosphocreatine concentration, leading to a higher rate of ATP resynthesis, a delay in the onset of muscular fatigue and a facilitated recovery during repeated bouts of high-intensity exercise.
International journal of sports medicine  •  1997  |  View Paper
Moreover, CMH and GAA supplementation increased the concentrations of creatine and phosphocreatine and the mRNA expressions of guanidinoacetate N-methyltransferase and creatine transporter in longissimus dorsi muscle, semitendinosus muscle, liver, or kidneys and decreased the mRNA expressions of arginine:glycine amidinotransferase in kidneys.
Journal of agricultural and food chemistry  •  2018  |  View Paper
Dietary supplementation with 1,200 mg/kg CMH increased the concentrations of Cr and PCr in PM muscle, and Cr in TA muscle than those in the 3-h transport group (P < 0.05).
Poultry science  •  2015  |  View Paper
Indeed, while creatine phosphate levels in meat from Duroc pigs increased in a dose-dependent manner with CMH supplementation, no effect was observed in meat from Landrace pigs.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2006  |  View Paper