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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phosphocreatine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ PCr pretreatment significantly reduced apoptosis, calcium and ROS production, induced by MGO, in NRK-52E cells.”
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.“Incubation of slices in high-potassium and ouabain media in aerobic conditions in the presence of Ca resulted in activation of respiration and glycolysis, decrease of ATP and phosphocreatine levels, and inhibition of amino acid incorporation into proteins.”
“ PCr reduced the amount of swelling induced by calcium by 20%.”
“ Creatine phosphate resynthesis was delayed by CA inhibition, whereas ATP replenishment was not affected.”
“ Calcium loading of a rat parotid microsomal fraction is greatly increased by an ATP-regenerating system ( phosphocreatine and creatine phosphokinase).”
“The removal of creatine phosphate (CP) greatly affected the Ca++ sensitivity and induced a leftward shift of the pCa++ tension curve.”
“0.45 unit over 2 hr while phosphocreatine concentrations decreased by ca.”
“Meanwhile, PCr can enhance calcium balance and reduce morphological pathological changes, ultimately, PCr helps to reduce apoptosis.”
Non-energy mechanism of phosphocreatine on the protection of cell survival.“ Creatine phosphate resynthesis was delayed by CA inhibition, whereas ATP replenishment was not affected.”
“The relaxation by phosphocrestine is reversed by calcium.”
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