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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phosphatidylinositol 4,5-Diphosphate
drug:
Pinacidil
Research Papers that Mention the Interaction
“… phosphatidylinositol 4,5-bisphosphate (PIP(2)) or phosphatidylinositol 3,4,… K(ATP) current activated by pinacidil and abolished the inhibitory effect of IGF-I. Thus, we show regulation of arterial K(ATP) channels … the first time that IGF-I inhibits these channels via a phosphoinositide 3-kinase-dependent pathway.”
Insulin-like growth factor-I inhibits rat arterial K(ATP) channels through pI 3-kinase.
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