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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phosphatidylinositol 4,5-Diphosphate
supplement:
Phosphatidylethanolamine
Research Papers that Mention the Interaction
“Mixed vesicles of PIP2 with phosphatidylcholine or phosphatidylethanolamine also inhibit CapZ, but addition of Triton X-100 both prevents and reverses PIP2's inhibition of CapZ.”
Regulation of CapZ, an actin capping protein of chicken muscle, by anionic phospholipids.“ PIP2 , together with either DAG or PE , synergistically stimulated phospholipase A2 activity by about 20-fold, and dramatically decreased the calcium concentration (from mM to nM) required for full activity of the enzyme.”
“The hydrolysis of PtdIns(4,5)P2 by membrane-bound PLC was increased when the substrate was mixed with phosphatidylethanolamine , phosphatidylcholine or various combinations of these with phosphatidylserine.”
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