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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Phosphatidylinositol 4,5-Diphosphate
drug:
Infliximab
Research Papers that Mention the Interaction
“ PIP2 and diacylglycerol mediate the release of Ca2þ from intracellular stores and the activation of protein kinase C, respectively.”
Second messengers in primary hypertension.“The enzymatic synthesis …,5-bisphosphate PtdIns (4,5)P2 ) was maximally enhanced by 0.… by micromolar concentrations of Ca2−. Inhibition of PtdIns and PtdIns4P kinase showed IC50 values for Ca2+ of 20 and 6 … of either Ca2+-induced activation of phospholipase C and polyphosphoinositide monophosphoesterases or low ATP concentrations.”
Phosphoinositide kinases in rat heart sarcolemma: biochemical properties and regulation by calcium
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