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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Possible Interaction: Phosphatidylinositol 4,5-Diphosphate and Adrenergic Alpha-1 Receptor Antagonists
Research Papers that Mention the Interaction
“Our data demonstrate that alpha1-adrenoceptor stimulation reduces the membrane PIP2 level, which in turn inhibits pinacidil-activated K(ATP) channels.”
Alpha1-adrenoceptor-mediated breakdown of phosphatidylinositol 4,5-bisphosphate inhibits pinacidil-activated ATP-sensitive K+ currents in rat ventricular myocytes.
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