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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phosphatidic Acid and Tyrosine

supplement:

Tyrosine

Research Papers that Mention the Interaction

Endogenous accumulation of PA by NaF treatment or exogenously added PA enhanced tyrosine phosphorylation of two proteins of 44 KDa (p44) and 47 KDa (p47) whereas tyrosine phosphorylation of other proteins was not affected.
Cellular signalling  •  1995  |  View Paper
Western analysis of immunoprecipitates indicated that PA induced the tyrosine phosphorylation of three distinct proteins involved in functional activation which co-immunoprecipitated in PA-stimulated cells.
Biochimica et biophysica acta  •  2000  |  View Paper
Unlike chemotaxis induced by zymosan-activated human serum, phosphatidate-induced chemotaxis was strongly inhibited by pretreatment of cells with herbimycin-A. Consistent with these observations, phosphatidic acid induced the tyrosine phosphorylation of several proteins as early as 10 s after stimulation.
Biochimica et biophysica acta  •  1997  |  View Paper