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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phosphatidic Acid
drug:
Gentamicin
Research Papers that Mention the Interaction
“Within 15 h of treatment with a single 100 mg/kg dose of gentamicin , significant increases in phosphatidylinositol and phosphatidic acid occurred, and further increases in these acidic phospholipids were seen 24 h after two and four daily doses.”
Alterations in renal cortical phospholipid content induced by gentamicin: time course, specificity, and subcellular localization.“In a companion paper (Mingeot-Leclercq et al. …), we showed that the inhibitory potency of gentamicin on the activity of lysosomal phospholipases, measured towards phosphatidylcholine included in … influenced by the nature of the acidic phospholipid used (phosphatidylinositol, phosphatidylserine, phosphatidic acid ), whereas the binding of the … of liposomes is similar.”
Effect of acidic phospholipids on the activity of lysosomal phospholipases and on their inhibition induced by aminoglycoside antibiotics--II. Conformational analysis.
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