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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenytoin
supplement:
Vitamin B 12
Research Papers that Mention the Interaction
“Conclusions: Our meta-analysis indicates that PHT monotherapy is associated with the increase in the serum homocysteine levels and decreased levels of folate and vitamin B12 , and hyperhomocysteinaemia may contribute to the acceleration of the atherosclerotic process.”
Effects of phenytoin on serum levels of homocysteine, vitamin B12, folate in patients with epilepsy“The experimental results have proved that a long-term phenytoin treatment significantly affects the concentration of Folate and Vitamin B12 among the Epileptic patients vigorously.”
To determine the effect of long-term antiepileptic drug on the serum folate and vitamin B12 among epileptic patients“The effect of combination of phenytoin with folic acid or folic acid and vitamin B12 is an interesting finding.”
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