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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phenytoin and Sodium Bicarbonate

Research Papers that Mention the Interaction

They emphasize that proprietary preparations of phenytoin are strongly alkaline in solution and infer that phenytoin depresses the folate absorption curve by raising the intraluminal pH in the upper small intestine and that this effect is mimicked by feeding sodium bicarbonate.
British medical journal  •  1971  |  View Paper
They emphasize that proprietary preparations of phenytoin are strongly alkaline in solution and infer that phenytoin depresses the folate absorption curve by raising the intraluminal pH in the upper small intestine and that this effect is mimicked by feeding sodium bicarbonate.
British medical journal  •  1971  |  View Paper
They emphasize that proprietary preparations of phenytoin are strongly alkaline in solution and infer that phenytoin depresses the folate absorption curve by raising the intraluminal pH in the upper small intestine and that this effect is mimicked by feeding sodium bicarbonate.
British medical journal  •  1971  |  View Paper