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Last Updated: 2 years ago

Possible Interaction: Phenytoin and Progesterone

supplement:

Progesterone

Research Papers that Mention the Interaction

Omission of Ca++ in the medium, or addition of a Ca++ channel blocker (D-600, 10(-4) M), of a calmodulin inhibitor (trifluoperazine, 30 microM) or of a calmodulin-dependent tubulin kinase inhibitor phenytoin , 50 microM), antagonized the stimulatory effect of progesterone.
Neuroendocrinology  •  1985  |  View Paper
Enzyme inducing AEDs such as phenobarbitone, phenytoin , carbamazepine, and oxcarbazepine increase the metabolism of orally administered estrogen (and progesterone to a lesser extent).
Annals of Indian Academy of Neurology  •  2015  |  View Paper