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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenytoin
supplement:
Polypeptides
Research Papers that Mention the Interaction
“Our previous studies concerning the molecular mechanisms of drug-induced gingival overgrowth have demonstrated that PHT alters the normal tissue turnover/wound healing signal by causing changes in macrophage phenotype, resulting in the upregulation of essential polypeptide growth factors such as platelet-derived growth factor (PDGF).”
Myofibroblasts in phenytoin-induced hyperplastic connective tissue in the rat and in human gingival overgrowth.“Several lines of evidence indicate that PH may exert its action through the modification of phosphorylation patterns of neuronal polypeptides.”
Effect of phenytoin on cytoskeletal protein phosphorylation and neuronal structure in the rat sensory cortex
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