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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phenytoin and Phosphatidic Acid

Research Papers that Mention the Interaction

Of the four antiepileptic drugs investigated in the present study, namely phenytoin, carbamazepine, phenobarbital, and valproate, only phenytoin blocked the acetylcholine-stimulated32P labeling of phosphatidylinositol and phosphatidic acid , and the acetylcholine-stimulated breakdown of polyphosphoinositides.
Neurochemical Research  •  2004  |  View Paper
Diphenylhydantoin , 0.3 mM, enhanced 45Ca2+ binding to phosphatidic acid and phosphatidylserine but not to sulfatide.
Journal of neurochemistry  •  1981  |  View Paper