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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenytoin
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“ Dietary iron reduces the anti-convulsion activity of PHT in a dose-dependent manner (0-6100 ppm).”
“The relationship between brain and plasma-unbound concentrations of PHT indicates that the penetration of PHT into brain is significantly inhibited by dietary iron.”
Dietary iron reduces the anti-convulsion activity of phenytoin in electroconvulsion via inhibition of brain penetration“The chemical structure of phenytoin indicates that there may be possible binding to iron ions.”
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