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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenylpropanolamine
supplement:
Yohimbine
Research Papers that Mention the Interaction
“Tyramine containing foods (red wine, liver, cheese) and nasal decongestants or diet aids containing phenylpropanolamine should be strictly avoided when yohimbine is used, to prevent a hypertensive crisis.”
Herbal remedies: renal tragedies.“Prazosin (2 mg/kg, SC) pretreatment did not significantly affect the potentiation of opioid antinociception by ephedrine and PPA , while yohimbine (4 mg/kg, SC) effectively antagonised this enhancing effect.”
Role of adrenoceptors in the potentiation of opioid antinociception by ephedrine and phenylpropanolamine in mice“ Yohimbine (5 mg/kg, ip), a selective alpha 2-adrenoreceptor antagonist, completely blocked the potentiating effect of phenylpropanolamine on carbon tetrachloride hepatotoxicity, providing further evidence that the increased hepatotoxic response with phenylpropanolamine cotreatment was mediated through alpha 2-adrenoreceptor stimulation.”
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