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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenylephrine
supplement:
Tyrosine
Research Papers that Mention the Interaction
“In cardiomyocytes cultured on ECM, PE stimulated a rapid increase in tyrosine phosphorylation of focal adhesion proteins including FAK, paxillin, and p130 Crk-associated substrate and subsequent formation of peripheral focal complexes.”
A Role for Focal Adhesion Kinase in Phenylephrine-induced Hypertrophy of Rat Ventricular Cardiomyocytes*“Immunoblot analysis of cell extracts with antiphosphotyrosine antibodies revealed that serotonin and phenylephrine also evoked an increase in tyrosine phosphorylation of several substrates.”
“The mechanism(s) accounting for the partial protection against hypertension reported here is unknown although administration of tyrosine was accompanied by a reduced cardiovascular responsiveness to graded doses of phenylephrine.”
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