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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenylephrine
supplement:
Phosphatidic Acid
Research Papers that Mention the Interaction
“We demonstrate that PLD1 activators, RhoA, and PKCα are critical for stress fiber formation and ERK activation, and enhance the production of phosphatidic acid PA ) upon phenylephrine addition.”
α1‐Adrenergic receptor‐induced cytoskeletal organization and cell motility in CCL39 fibroblasts requires phospholipase D1“As evidence for …, we found that phenylephrine … phosphatidic acid and phosphatidylinositol, 2) generation of [3H]inositol phosphates from prelabeled [3H]inositol phospholipids, 3) cytosolic Ca2+, and 4) membrane-bound … dose-related increases in [3H]-DOG uptake that were similar in magnitude and time course to those induced by insulin.”
“Under our experimental conditions, several adrenergic drugs, including DL-propranolol, phentolamine, isoproterenol, phenylephrine , but not sotalol, increased markedly (nearly up to 5-fold) the 32Pi incorporation into PhA and PhI of the iris.”
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