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“3 Inversely, treatment of phenylephrine (10 μM)‐stimulated VSMCs with NDGA induced DNA fragmentation in a dose‐dependent fashion.”
“Nordihydroguaiaretic acid NDGA ), a lipoxygenase inhibitor, caused 36 and 50% decrease in phenylephrine (10 μM)‐stimulated [3H]‐thymidine incorporation at concentrations of 1 μM and 10 μM respectively.”
British journal of pharmacology • 1997 | View Paper
“The lipoxygenase inhibitor, nordihydroguaiaretic acid (10 microM), not only decreased sensitivity to serotonin and phenylephrine , but eliminated the preload effect as well.”