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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenylephrine
supplement:
Kaempferol
Research Papers that Mention the Interaction
“Of the chemical constituents of SJW tested hyperforin but not hypericin or the flavonoids quercitrin, rutin and kaempferol inhibited phenylephrine induced contractions.”
Effects of the antidepressant St. John's wort (Hypericum perforatum) on rat and human vas deferens contractility.“Although, neither chrysin nor luteolin affected ACh impaired vasodilatation, they both alleviated exaggerated vasoconstrictions to PE and KCl in IR animals.”
Chrysin and luteolin alleviate vascular complications associated with insulin resistance mainly through PPAR-γ activation.“ Luteolin (CE50: 1.5μg/ml), chrysoeriol (CE50: 13.2μg/ml) and p-coumaric acid (CE50: 95.2μg/ml), isolated from the aqueous extract, caused dilatation of thoracic aortic rings pre-contracted with phenylephrine.”
“ Luteolin evoked a concentration-dependent relaxation in aortic rings previously contracted by phenylephrine , and the pD(2) value was 5.24+/-0.04.”
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