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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenylephrine
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The activation of alpha 1-adrenergic receptors phenylephrine ) caused an increase in the blood concentrations of ACTH and cortisol, whereas the blockade of alpha 1-adrenergic receptors (prazosin) induced an essential decrease in the concentrations of these hormones in blood of the persons investigated at various age.”
[Effect of pharmacological stimulation and blockade of alpha-adrenergic receptors on adrenocorticotropic hormone and cortisol in the blood of people of various age].“considerably reduced ACTH and corticosterone secretion induced by phenylephrine (30 microg i.c.v.),”
Nitric oxide in the adrenergic-and CRH-induced activation of hypothalamic-pituitary-adrenal axis.“The alpha-agonist phenylephrine also increased the ACTH level.”
“In contrast, the combination of ACTH and phenylephrine was additive.”
“Epinephrine, norepinephrine, phenylephrine , clonidine, B-HT933, and B-HT920 caused a significant and dose-related increase of the ACTH concentration in the serum.”
“Norepinephrine, epinephrine and clonidine, but not methoxamine and phenylephrine inhibited ACTH secretion.”
“Both methozamine and phenylephrine lowered the very high levels of cyclic AMP that were produced by high concentrations of isoproterenol (10 muM) or ACTH (100 MU/ml), and partially inhibited lipolysis.”
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