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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phenylalanine
drug:
Uracil
Research Papers that Mention the Interaction
“All actively transported substances tested including L-phenylalanine , L-leucine, D-galactose, D-glucose, and 3-O-methylglucose inhibited the transport of uracil.”
Inhibition of the intestinal transport of uracil by hexoses and amino acids.“When small molecules are hydrogen bound to uracil, addition of the phenylalanine ring can increase or decrease the acidity of uracil depending on the number and nature (acidity) of the molecules bound.”
“When phenylalanine is complexed with isolated uracil , the proton affinity of all acceptor sites significantly increases (by up to 28 kJ mol(-1)), while the N1 acidity slightly decreases (by ~6 kJ mol(-1)).”
Combined effects of π-π stacking and hydrogen bonding on the (N1) acidity of uracil and hydrolysis of 2'-deoxyuridine.
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