Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Phenylalanine and Ubiquinone

supplement:

Phenylalanine

supplement:

Ubiquinone

Research Papers that Mention the Interaction

Phenylalanine has been shown to inhibit the activities of both 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase, enzymes common to both cholesterol and CoQ10 biosynthesis.
Mitochondrion  •  2007  |  View Paper
Significantly negative correlation was observed between ubiquinone-10 and phenylalanine (r = -0.441; p < 0.05).
Clinical biochemistry  •  2002  |  View Paper
Phenylalanine , added to the mixture, stimulated the biosynthesis of ubiquinone and ubichromenol in the liver tissue preparations.
Voprosy meditsinskoi khimii  •  1976  |  View Paper