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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phenylalanine
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“Replacement of this tyrosine by phenylalanine (Y616F) disabled the auto-phosphorylation activity of Fer and abolished its ability to phosphorylate Stat3.”
Hsp90 and a tyrosine embedded in the Hsp90 recognition loop are required for the Fer tyrosine kinase activity.“Preferential utilization of glucose-1-phosphate, d-mannitol and l-phenylalanine ; production of 2-hydroxycaproic acid and termination of dimethyl sulphide production were major Fnn response-factors to iron limitation.”
The effects of iron limitation and cell density on prokaryotic metabolism and gene expression: Excerpts from Fusobacterium necrophorum strain 774 (sheep isolate).“Exchange of tyrosine residues 421, 466, and 482 for phenylalanine prevented cortactin phosphorylation by hypertonicity and strongly decreased it upon FER overexpression, suggesting that FER targets primarily the same osmo-sensitive tyrosines.”
“Thus, the large benzyl side chain of phenylalanine at position 68 inhibits the rate of ligand movement up to and away from the iron atom but not the final bound state.”
“We conclude that iron participates in the hydroxylation of phenylalanine.”
Phenylalanine Hydroxylase from Chromobacterium violaceum“ Phenylalanine , tyrosine, and tryptophan inhibit the activation of the enzyme by iron in a competitive fashion.”
“The alteration of the environment of the iron atom of cytochrome c by movement of the swinging phenylalanine ring can be described as variable space-filling.”
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