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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phenylalanine and Glutamate

supplement:

Phenylalanine

supplement:

Glutamate

Research Papers that Mention the Interaction

Mutating an N-terminal domain amino acid, leucine 256, to phenylalanine increased the EC50 for l-glutamate to 92.2 ± 3.5 μM, and reduced the Hill number from 1.89 ± 0.35 to 1.09 ± 0.16.
Molecular Pharmacology  •  2009  |  View Paper
Substrate specificity of the purified enzyme was modified in the presence of 6-azauracil or phenylalanine resulting in decreased specificity to L-glutamate and increased specificity to L-aspartate.
Biochimica et biophysica acta  •  1977  |  View Paper