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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phentolamine
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The concentration of ACTH in fetal plasma was increased by adrenaline and to a lesser extent by noradrenaline and methoxamine; these were blocked by phentolamine.”
The metabolic and endocrine effects of circulating catecholamines in fetal sheep.“ Phentolamine , an alpha-adrenergic antagonist, blocks the bulk of magnesium accumulation stimulated by native ACTH and norepinephrine; propranolol, a beta-adrenergic antagonist, blocks the earliest phase of Mg2+ uptake by these hormones but has little effect on net uptake.”
“Lipolysis, stimulated by noradrenaline, isoproterenol, or ACTH , was inhibited dose-dependently by phentolamine.”
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