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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Phenoxybenzamine and Progesterone

Research Papers that Mention the Interaction

The increase of hypothalamic cAMP observed at 4h of progesterone injection was blocked by the administration of an alpha(phenoxybenzamine ) or a beta-adrenoblocker (propranolol) suggesting the participation of both, alpha and beta adrenergic receptors.
Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia  •  1993  |  View Paper
Phenoxybenzamine (0.8, 4.0 and 20.0 mg/kg), propranolol (0.8, 4.0 and 20.0 mg/kg) and prazosin (0.2 and 1.0 mg/kg) caused a dose-dependent reduction of progesterone induced lordosis.
Pharmacology Biochemistry and Behavior  •  1985  |  View Paper
On the other hand, the adminitration of phenoxybenzamine prior to progesterone , blocked the steroid effect on LH without inhibiting the plasma NE rise.
Neuroendocrinology  •  1980  |  View Paper