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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenoxybenzamine
supplement:
Progesterone
Research Papers that Mention the Interaction
“The increase of hypothalamic cAMP observed at 4h of progesterone injection was blocked by the administration of an alpha(phenoxybenzamine ) or a beta-adrenoblocker (propranolol) suggesting the participation of both, alpha and beta adrenergic receptors.”
Effect of progesterone on the hypothalamic cAMP concentration in estradiol-primed rats.“ Phenoxybenzamine (0.8, 4.0 and 20.0 mg/kg), propranolol (0.8, 4.0 and 20.0 mg/kg) and prazosin (0.2 and 1.0 mg/kg) caused a dose-dependent reduction of progesterone induced lordosis.”
“On the other hand, the adminitration of phenoxybenzamine prior to progesterone , blocked the steroid effect on LH without inhibiting the plasma NE rise.”
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