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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenoxybenzamine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“In addition, the phasic and tonic components of the response to (-)-norepinephrine, which are mediated by the mobilization of intracellular calcium and the translocation of extracellular calcium, respectively, are also inhibited to the same extent by phenoxybenzamine.”
Activation of a single alpha-1-adrenoceptor subtype in rat aorta mobilizes intracellular and extracellular pools of calcium.“Sympathetic inhibition attempted by a combination of adrenalectomy, reserpinization, phenoxybenzamine hydrochloride and propanolol significantly diminished TDLF after calcium (P < 0.001).”
“In phenoxybenzamine‐ or phentolamine‐treated spleens, stimulation of the nerves in the presence of calcium evoked a secretory response which was comparable to the one produced by introduction of calcium after a few minutes of nerve stimulation.”
“The depolarization-induced exocytosis, which is stimulated by calcium, may be affected by prostaglandin E(2) or phenoxybenzamine through inhibition or enhancement of the actions of calcium in the release process.”
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