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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Phenobarbital and Polypeptides

Research Papers that Mention the Interaction

The levels of the two mRNAs encoding these polypeptides were increased substantially upon phenobarbital administration.
Biochemistry  •  1986  |  View Paper
The amount of functional mRNA specific for the P-450 polypeptides increases dramatically in response to an acute administration of phenobarbital ; however, in untreated rats the amount of functional mRNA was below the level of detection by the translational assay.
Archives of biochemistry and biophysics  •  1983  |  View Paper
A number of major microsomal polypeptides which might represent unidentified forms of cytochrome P-450 in untreated males and females were markedly decreased in a specific manner as a result of phenobarbital and/or 3-methylcholanthrene treatments.
Archives of biochemistry and biophysics  •  1982  |  View Paper
Noncoplanar isomers and PB induced the synthesis of a polypeptide of approximate 51,000 daltons.
Life sciences  •  1980  |  View Paper
Administration of phenobarbital , or of benzo[a]pyrene or 3-methylcholanthrene, resulted in specific increases of membrane polypeptides corresponding to cytochrome P-450 and cytochrome P-448 species respectively.
Biochemical and biophysical research communications  •  1976  |  View Paper