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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phenethyl Isothiocyanate
supplement:
Xanthohumol
Research Papers that Mention the Interaction
“Modulation of the activity of NF-κB and Nrf2 by the combination of XAN and PEITC was found to lead to reduced proliferation of PANC-1 cells.”
“The combination of XAN and PEITC also enhanced the activation and expression of Nrf2 and subsequently the expression of GSTP, NQO1, and SOD genes which are controlled by this transcription factor.”
“The combination of XAN and PEITC was more efficient than the single compounds in reducing the binding of NF-κB p65 subunits by 47-60% and expression of p65 gene by 28-48%.”
“These results suggest that the combination of XAN and PEITC might be considered as a novel strategy for the prophylaxis and/or treatment of PC.”
Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells.“The combinations of XAN with PEITC and RES with PEITC increased mostly the expression of SOD, GSTP, CAT, and GPx.”
“ XAN and PEITC mixture induced the cell cycle arrest in G0/G1 phase and increased apoptotic and autophagy markers.”
Combinations of Phytochemicals More Efficiently than Single Components Activate Nrf2 and Induce the Expression of Antioxidant Enzymes in Pancreatic Cancer Cells.
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