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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phenethyl Isothiocyanate and Chemopreventive Agent

Research Papers that Mention the Interaction

Our data show that PEITC exerts its inhibitory effect on pancreatic cancer cells through several mechanisms, including G2/M phase cell cycle arrest and induction of apoptosis, and supports further investigation of PEITC as a chemopreventive agent for pancreatic cancer.
Nutrition and cancer  •  2014  |  View Paper
It is concluded that: (a) … human liver, and (b) PEITC , at concentrations that can be achieved by dietary intake, can antagonise the carcinogenicity of chemicals which rely on the … heterocyclic amines and polycyclic aromatic hydrocarbons, and this is likely to be a major contributory mechanism to its chemopreventive activity.
Toxicology  •  2010  |  View Paper
The results of this study support our hypothesis that PEITC inhibits this oxidative metabolism of NNK in humans, as seen in rodents, and support further development of PEITC as a chemopreventive agent against lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology  •  1995  |  View Paper