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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenacetin
supplement:
Genistein
Research Papers that Mention the Interaction
“The interaction studies showed that genistein inhibited formation of acetaminophen from phenacetin with an IC50 value of 16 microM. Additional studies showed that phenacetin and genistein were mutually inhibitory.”
Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones.
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