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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phenacetin
supplement:
Angelicin
Research Papers that Mention the Interaction
“Coadministration with PRN or IPRN significantly inhibited cyp1a2 activity in rats, with the area under the curve (AUC) of phenacetin increasing more than 5-fold.”
“ IPRN , on the other hand, would result in 3.24- and 5.01-fold increases in phenacetin AUCs in healthy volunteers and smokers, respectively.”
Identification and Characterization of Psoralen and Isopsoralen as Potent CYP1A2 Reversible and Time-Dependent Inhibitors in Human and Rat Preclinical Studies
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