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Last Updated: 3 years ago

Possible Interaction: Perhexiline and Long Chain Fatty Acid

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drug:

Perhexiline

supplement:

Long Chain Fatty Acid

Research Papers that Mention the Interaction

“The antianginal agent perhexiline inhibits rat cardiac carnitine palmitoyltransferase-1 (CPT-1) and CPT-2, key enzymes for mitochondrial transport of long-chain fatty acids.”

Dissociation Between Metabolic and Efficiency Effects of Perhexiline in Normoxic Rat Myocardium

Journal of cardiovascular pharmacology • 2005 | View Paper

“ Perhexiline is a potent prophylactic anti-anginal agent that has been shown to inhibit myocardial utilization of long-chain fatty acids and to inhibit the mitochondrial enzyme carnitine palmitoyltransferase (CPT)-1.”

Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart.

Journal of cardiovascular pharmacology • 2000 | View Paper

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