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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Pentoxifylline
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Intact PTH, ALP, Ca , P, BALP and DPYD levels were reduced significantly after PTX (intact PTH, p = 0.003, Ca, p = 0.0005, P, p = 0.0393, ALP, p = 0.0051, DPYD, p = 0.0232, BALP, p = 0.0324).”
Assessment of therapeutic effect in patients with secondary hyperparathyroidism using bone scintigraphy“Conclusions: Bone mass increases after PTX for PHPT in patients receiving oral calcium.”
“In this study, we found that PTX significantly reduced levels of PTH, calcium and phosphate.”
“ PTX treatment also resulted in an increase in intracellular calcium (Ca(2+)) level.”
“ PTX reduced serum total Ca from 2.79 ± 0.13 to 2.39 ± 0.09 mmol/l (p < 0.001) and tended to reduce IVST [10.6 ± 2.1 vs. 10.4 ± 2.0 mm; not significant (n.s.)],”
“Reduction in the exchangeable calcium pool may explain the clinical finding that extraosseous calcifications regress in some patients after PTX.”
“Urinary excretion of calcium was unusually low before and immediately after PTX , and later during an inadvertent vitamin D intoxication.”
“ Pentoxifylline (0.5 mmol/l) modulates the effect of Ca2+ (conc.”
“ PTX (10 nM) induced a sustained rise in cytosolic Ca2+ ([Ca2+]i), which was resistant to verapamil but suppressed by omission of extracellular Ca2+.”
Characteristics of palytoxin-induced cation currents and Ca2+ mobilization in smooth muscle cells of rabbit portal vein“ Ionized blood calcium values (Ca2+) were significantly (P = 0.014) lower in PTX dogs (1.31 +/- 0.01 mmol/L) than in control dogs (1.36 +/- 0.00 mmol/L), but were more variable in PTX dogs.”
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