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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Pentostatin
supplement:
S-Adenosylmethionine
Research Papers that Mention the Interaction
“Infusion of dCF resulted in increases of up to 20-fold in the concentration of AdoHcy in circulating lymphoblasts, causing a decrease in the S-adenosylmethionine :AdoHcy ratio (the "methylation index") from a pretreatment value of greater than 40:1 to less than 4:1.”
S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
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