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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Pentobarbital
supplement:
Vitamin C
Research Papers that Mention the Interaction
“Catalepsy induced by haloperidol (0.25 mg/kg IP) was attenuated by ascorbic acid (50–200 mg/kg IP) while pentobarbitone (20 mg/kg IP)-induced sleep in rats was dose-dependently antagonised by ascorbic acid (50–400 mg/kg IP).”
Some behavioural and EEG effects of ascorbic acid in rats“Both doses of AA given IP after SP anesthesia significantly prolonged sleeping time.”
Pharmacologic doses of ascorbic acid prolong the effects of pentobarbital anesthesia.“ Ascorbic acid can reduce the inhibition produced by pentobarbital in the oxidation of carbohydrate by rat brain in vitro.”
The effect of ascorbic acid in reducing the inhibition of brain metabolism produced by pentobarbital in vitro.
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