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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Penicillins
supplement:
Threonine
Research Papers that Mention the Interaction
“Minimum inhibitory concentrations of beta-lactam antibiotics showed that the presence of threonine at position 237 exerted a dominant effect increasing the enzymes' preference for various early generation cephalosporins over penicillins.”
Substitution of Thr for Ala-237 in TEM-17, TEM-12 and TEM-26: alterations in beta-lactam resistance conferred on Escherichia coli.“Upon addition of methionine, methionine sulfoxide, and threonine , there occurs a marked enhancement of penicillin susceptibility of broth cultures of Brucella, Eberthella, Salmonella, and Shigella.”
“ Penicillin susceptibility of highly refractory Gramnegative organisms may be greatly enhanced upon addition of methionine, threonine and methionine sulfoxide.”
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