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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Penicillins and Sodium Bicarbonate

Research Papers that Mention the Interaction

Sodium bicarbonate ingested with or prior to penicillin (1, 5, 15) failed to protect most of the drug from destruction.
The Ohio journal of science  •  1946  |  View Paper
Combinations of sodium bicarbonate , colloidal kaolin, magnesium trisilicate, and bismuth subcarbonate with penicillin produce a higher penicillin titer in the urine than the various antacids and buffers recommended for oral penicillin therapy.
Science  •  1946  |  View Paper
Addition of NaHCO3 significantly increased the catalytic efficiency against penicillins , but not against ceftazidime.
The Journal of antimicrobial chemotherapy  •  2016  |  View Paper
Combinations of sodium bicarbonate , colloidal kaolin, magnesium trisilicate, and bismuth subcarbonate with penicillin produce a higher penicillin titer in the urine than the various antacids and buffers recommended for oral penicillin therapy.
Science  •  1946  |  View Paper