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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Penicillins
supplement:
Sodium Bicarbonate
Research Papers that Mention the Interaction
“ Sodium bicarbonate ingested with or prior to penicillin (1, 5, 15) failed to protect most of the drug from destruction.”
The urinary excretion of penicillin after ingestion with and without adjuvants and following intramuscular infection.“Combinations of sodium bicarbonate , colloidal kaolin, magnesium trisilicate, and bismuth subcarbonate with penicillin produce a higher penicillin titer in the urine than the various antacids and buffers recommended for oral penicillin therapy.”
“Addition of NaHCO3 significantly increased the catalytic efficiency against penicillins , but not against ceftazidime.”
Structural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 β-lactamase in Pseudomonas aeruginosa.“Combinations of sodium bicarbonate , colloidal kaolin, magnesium trisilicate, and bismuth subcarbonate with penicillin produce a higher penicillin titer in the urine than the various antacids and buffers recommended for oral penicillin therapy.”
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