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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Pemetrexed
supplement:
Kanglaite
Research Papers that Mention the Interaction
“Concomitant administration in both cell lines indicated that the cytotoxic interactions between KLT and pemetrexed were schedule-dependent.”
“Signaling pathway analysis showed that exposure to pemetrexed resulted in increased phospho-p44/42MAPK levels which were inhibited by subsequent exposure to KLT.”
“The administration of pemetrexed followed by KLT had a synergistic effect and an advantage over KLT followed by pemetrexed.”
“We investigated the mechanism underlying the cytotoxic synergy between KLT and pemetrexed in NSCLC cell lines.”
The Synergistic Mechanism of Pemetrexed Followed by Kanglaite was due to KLT Subsequently Inhibiting the Pemetrexed-Activated MAPK Signaling Pathway.
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