supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Pemetrexed
supplement:
Kanglaite
Research Papers that Mention the Interaction
“Concomitant administration in both cell lines indicated that the cytotoxic interactions between KLT and pemetrexed were schedule-dependent.”
“Signaling pathway analysis showed that exposure to pemetrexed resulted in increased phospho-p44/42MAPK levels which were inhibited by subsequent exposure to KLT.”
“The administration of pemetrexed followed by KLT had a synergistic effect and an advantage over KLT followed by pemetrexed.”
“We investigated the mechanism underlying the cytotoxic synergy between KLT and pemetrexed in NSCLC cell lines.”
The Synergistic Mechanism of Pemetrexed Followed by Kanglaite was due to KLT Subsequently Inhibiting the Pemetrexed-Activated MAPK Signaling Pathway.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback