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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Parthenolide
supplement:
Selenocysteine
Research Papers that Mention the Interaction
“ PTL selectively targets the selenocysteine residue in TrxR1 to inhibit the enzyme function, and further shifts the enzyme to an NADPH oxidase to generate superoxide anions, leading to reactive oxygen species accumulation and oxidized thioredoxin.”
Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells*
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