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Last Updated: 3 years ago

Possible Interaction: Paromomycin and Magnesium Cation

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drug:

Paromomycin

supplement:

Magnesium Cation

Research Papers that Mention the Interaction

“ Paromomycin binding , unlike dihydrostreptomycin binding, is independent of changes in ribosome concentration but influenced by magnesium ion concentration.”

Paromomycin and dihydrostreptomycin binding to Escherichia coli ribosomes.

European journal of biochemistry • 1976 | View Paper

“Paromomycin, at the ribosomal level, prevents the attachment of amino acyl-…-RNA and causes accumulation of m-RNA.Divalent cations (Ca++ and Mg++ ) antagonize the bactericidal action of paromomycin and interfere with the in vivo binding of the antibiotic on both the cell surface and the intracellular binding sites.”

The mode of action of the antibiotic paromomycin on Staphylococcus aureus.

Canadian journal of microbiology • 1966 | View Paper

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