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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Paricalcitol
drug:
Aliskiren
Research Papers that Mention the Interaction
“Taken together, a treatment combining aliskiren with paricalcitol better inhibits UUO-induced renal injury.”
Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin“Although combination therapy showed no additional effect on oxidative system, renin-angiotensin system and renal histology, aliskiren plus paricalcitol significantly decreased interstitial fibrosis volume when compared to monotherapy (Group A+P vs Group A, p<0.005; Group A+P vs Group P, p=0.002).”
“Conclusion: Our data seem to suggest a potential role of aliskiren plus paricalcitol acting synergystically for reducing the progression of diabetic nephropathy in an experimental rat model.”
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