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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Pargyline and Tyrosine

supplement:

Tyrosine

Research Papers that Mention the Interaction

Systemic injections of m-tyrosine (50-150 mg/kg) 30 min after the administration of pargyline (75 mg/kg) produced intense behavioural stimulation which was not evident after injection of either compound alone.
The increase in levels of m-tyramine produced by m-tyrosine plus pargyline was 10 times greater than that produced by m-tyrosine alone, whereas the depletion in levels of the more abundant amines was not potentiated by pargyline pretreatment.
European journal of pharmacology  •  1982  |  View Paper
Low doses of both tryptamine and 5-hydroxytryptamine, in the presence of pargyline , increase the activities of tyrosine and tryptophan aminotransferases and phosphoenol- pyruvate carboxykinase; these effects are distinct from those of the parent aminoacid.
Biochemical pharmacology  •  1979  |  View Paper