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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Para-aminobenzoic acid (PABA)
drug:
Sulfathiazole
Research Papers that Mention the Interaction
“It has already been demonstrated by Katznelson and Gooderham (1949) that para-aminobenzoic acid reverses the effect of sulfathiazole in the apiary.”
THE INFLUENCE OF ANTIBIOTICS AND SULFA DRUGS ON BACILLUS LARVAE, CAUSE OF AMERICAN FOULBROOD OF THE HONEYBEE, IN VITRO AND IN VIVO“The concentration of the dihydrofolic acid precursor para-aminobenzoic acid (pABA) increased with growth and with concentrations of the competitor STA.”
Identification and dynamic modeling of biomarkers for bacterial uptake and effect of sulfonamide antimicrobials.“Inhibition of growth by sulphathiazole was overcome competitively by p-aminobenzoic acid.”
“ Sulphathiazole inhibited the synthesis of both factors, the inhibition being overcome competitively by p-aminobenzoic acid.”
“In two previous reports, it was shown that cocarboxylase and p-aminobenzoic acid counteract the inhibitory effect of sulfathiazole on yeast and bacterial carboxylases.”
“Whereas cocarboxylase brings about this effect without exercising any inhibitory action on carboxylase, p-aminobenzoic acid exercises the antagonistic action to sulfathiazole while maintaining a certain degree of inhibitory effect of its own on carboxylases.”
“Wiedling (1941) found that para-aminobenzoic acid produced an inhibition of the effect of sulfanilamide, sulfapyridine and sulfathiazole on the fresh water diatom Nitzschia palea var.”
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