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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Para-aminobenzoic acid (PABA) and Sulfamethazine

Research Papers that Mention the Interaction

The effect of testicular hypertrophy appears to be independent of bacteriostatic action as it is produced by 2-phenysulphonylamido-4:6-dimethylpyrimidine, and the effect of sulphadimidine is not neutralized by administration of p-aminobenzoic acid or of folic acid.
Proceedings of the Royal Society of London. Series B - Biological Sciences  •  1952  |  View Paper
PABA at a concentration of 10 µg ml−1 completely reversed the inhibitory activity of SMZ and enabled reliable identification of SMZ in the examined samples.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment  •  2009  |  View Paper
SMZ is a structural analog and competitive antagonist to p-aminobenzoic acid (PABA), which is a precursor of folates.
Plant Cell  •  2012  |  View Paper