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“In simple nutritional experiments, the amount of PGA required to replace PABA is much greater than expected on a molecular basis (Lampen and Jones, 1947; Sarett, 1947, 1951).”
“With Tetrahymena pyriformis (geleii), it is shown that thymine (or thymidine), glycine, p-amino-benzoic acid , creatin and vitamin B12 diminish the requirement for folic acid.”