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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Papaverine
supplement:
Quinine
Research Papers that Mention the Interaction
“Four weeks of … combination of quinine … papaverine at a dose of 3 X 1 coated tablet per day cause a marked and--as compared with placebo--statistically highly … than 0.01) in cerebral blood flow of patients with a moderate impairment of the terminal vascular system of the brain.”
[Treatment of cerebral circulatory insufficiency. Double-blind study of the efficacy of a quinine-papaverine combination].“Pre-treatment with PAP increased intracellular cAMP and nicotinamide adenine dinucleotide (NAD+) levels, restored mitochondrial membrane potential (ΔΨm), and decreased ROS and caspase 3/7 content in QUIN exposed neurons.”
Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons.
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