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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Papain
Research Papers that Mention the Interaction
“The purified protein inhibits papain and bromelain, does not correct the clotting time of a kininogen-depleted human plasma, and does not affect the clotting time of plasma from Waglerophis merremii, a nonpoisonous snake; the same type of inhibitor was found in this nonpoisonous snake.”
A Bothrops jararaca plasma cysteine-proteinase inhibitor related to mammalian kininogen.“The purified protein inhibited papain and ficin but not cathepsin B, cathepsin H, trypsin, or chymotrypsin.”
“… purified protein exhibited … papain with a Ki of 5 X 10(-11) M. As shown by immunochemical quantitation as well as functional activity, a 6-10-fold … 1-cysteine cysteine proteinase inhibitor content was recorded in inflammatory serum, thus demonstrating the protein to be a typical acute phase reactant.”
Rat alpha 1-cysteine proteinase inhibitor. An acute phase reactant identical with alpha 1 acute phase globulin.“… purified protein showed strong … activities against papain (Ki: 3.7 x 10(-8) M), and cathepsins H (Ki: 5.7 x 10(-9) M) and L (Ki: 1.7 x 10(-8) M), whereas it inhibited cathepsin B to a lesser extent (Ki: 2.9 x 10(-7) M).”
Corn cystatin I expressed in Escherichia coli: investigation of its inhibitory profile and occurrence in corn kernels.
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